Author

Rosa F. Hwang

The University of Texas MD Anderson Cancer CenterORCID 0000-0002-3103-6511Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Organism:mouse· 1 Assay:organoid / primary culture· 1 Assay:proteomics· 1

Frequent Co-Authors

Alica K. Beutel· 1 shared Antoine A. RuzetteiD· 1 shared Boryana PetrovaiD· 1 shared Byanjana Thapa· 1 shared Christopher J. HalbrookiD· 1 shared David Kuang-Fu ChangiD· 1 shared Hanna E. SeppäneniD· 1 shared Hanna M. DohiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperCancer Biology

Alica K. Beutel

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Therapeutic Eradication of Cancer-associated Fibroblasts Inhibits in vivo progression of Pancreatic Cancer

Matilda Roos-Mattila, Harri K. Mustonen, Markus J. V. Vähä-Koskela, Sonja Boyd, Sanna Vainionpää, Rosa F. Hwang, Pauli Antero Puolakkainen, Vadim Le Joncour, Pirjo Maarit Laakkonen, Hanna E. Seppänen

This study shows that clemastine eradicates cancer-associated fibroblasts, halts pancreatic cancer progression, and synergizes with gemcitabine to inhibit metastasis.

bioRxiv · Nov 4, 2025 · PreprintCancer Biology

A novel DNA repair protein, N-Myc downstream regulated gene 1 (NDRG1), links stromal tumour microenvironment to chemoresistance

Nina V. Kozlova, Kayla A. Cruz, Hanna M. Doh, Antoine A. Ruzette, Nicholas A. Willis, Su Min Hong, Raul S. González, Monika Vyas, Laura M. Selfors, Stephan B. Dreyer, Rosanna Upstill‐Goddard, Kerrie L Faia, Steve Wenglowsky, Joshua Close, Alica K. Beutel, , Taru E. Muranen

This study identifies NDRG1 as a DNA repair protein that links pancreatic cancer stroma to chemoresistance by enhancing DNA damage repair through R-loop resolution.

bioRxiv · Jan 22, 2025 · PreprintCancer Biology