Rainer Surges

This study uses single-cell transcriptomics to show that BRAFV600E-driven glioneuronal tumors have distinct immune profiles based on tumor grade, with SPP1 playing a key role in high-grade tumors.

This study shows that gangliogliomas induce developmental changes in cortical networks, leading to seizure dynamics that shift from neonatal to adult stages, with age-specific therapeutic implications.

This study uses Bayesian heart-rate entropy to analyze autonomic dynamics during seizures, finding that seizure duration, not awareness, is the strongest correlate of entropy changes.

This study identifies human medial temporal lobe neurons that encode future rewards and intertemporal choices, showing reduced temporal coding in impulsive individuals.

This study shows that sleep ripples drive single-neuron reactivation in humans, supporting memory consolidation and highlighting sleep's role in stabilizing memories.

This study evaluates photopharmacology agents in human and mouse brain tissue to control epilepsy, finding that caged propofol suppresses epileptiform activity across species.

The paper shows that during sleep, hippocampal sharp wave-ripples reactivate memory-related neurons and interact with cortical slow oscillations to support memory consolidation.

This study shows that attention modulates hippocampal sharp-wave ripples in humans, with higher frequency during high attention and increased phase synchrony during low attention.

This study investigates semantic tuning of concept cells in the human medial temporal lobe, finding graded responses and region-specific categorical profiles.

This study examines how theta-gamma-spike interactions coordinate sequential memory in the human medial temporal lobe during encoding and memory maintenance.

This study identifies region-specific spreading depolarization as a key factor in post-ictal behavioral abnormalities in epilepsy using mouse and human data.

The paper investigates the role of hippocampal P3 in the attentional blink by analyzing intracranial recordings from patients performing an RSVP task, finding that T1-related P3 amplitudes and latencies correlate with T2 processing outcomes.

The paper shows how slow oscillations, spindles, and ripples coordinate to enhance neuronal firing rates, cross-correlations, and cross-regional interactions during human sleep.

The paper examines how auditory beat stimulation affects memory-related neuron activity in the human medial temporal lobe, finding negative correlations between beat stimulation and memory performance in specific brain regions.