Author

Ashley A. Moore

Northwestern UniversityORCID 0009-0002-8459-7264Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Assay:ATAC-seq· 1 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Organism:human· 1

Frequent Co-Authors

Ami Siddharth BhattiD· 2 shared Aaron A. BehriD· 1 shared Anne BrunetiD· 1 shared Aravind NatarajaniD· 1 shared Boryana DoyleiD· 1 shared Daniel J. RichardiD· 1 shared Erin F. BrooksiD· 1 shared Gabriella Z. M. ReynoldsiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersMicrobiology

Ami Siddharth BhattORCID

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2 papers

Recent·Most cited

Replicative selfish genetic elements are driving rapid pathogenic adaptation of Enterococcus faecium

Matthew P. Grieshop, Aaron A. Behr, Sierra Bowden, Jordan D. Lin, Marco Molari, Gabriella Z. M. Reynolds, Erin F. Brooks, Boryana Doyle, Ashley A. Moore, Guillermo Rodriguez Nava, Jorge Luis Salinas, Niaz Banaei, Ami Siddharth Bhatt

This study identifies ISL3 elements as drivers of rapid genomic evolution in E. faecium, enabling metabolic adaptation in clinical settings through structural variation and gene regulation.

Nature · Apr 22, 2026Peer-reviewedMicrobiology

Age-related microbiome metabolites alter RNA splicing and chromatin accessibility in the brain

Meenakshi Chakraborty, Sophia M. Shi, Imani E. Porter, Daniel J. Richard, Georgi K. Marinov, Mukundh N. Murthy, Ashley A. Moore, Jenna Lynn Elizabeth Blum, Aravind Natarajan, James W.S. Jahng, Joseph C. Wu, Sydney X. Lu, Shawn M. Davidson, William James Greenleaf, Nay Lui Saw, , Ami Siddharth Bhatt

The paper identifies age-related microbiome metabolites that alter RNA splicing and chromatin accessibility in the mouse brain using metabolomics, transcriptomic, and multi-omic approaches.

bioRxiv · Oct 3, 2025 · PreprintNeuroscience