Author
Stanford MedicineORCID 0000-0003-0301-4259Unclaimed ORCID profile · follow to get notified of new preprints
Mutual co-authors in cluster
6 papers
Recent·Most cited
Mark Ragheb, Yuya Kiguchi, Jordan D. Lin…·Ami Siddharth Bhatt
The paper identifies immunomodulatory bacterial microproteins from Leptotrichia using a microproteome screen and shows they influence macrophage polarization.
Matt W.G. Walker, Egill Richard, Tanner Wiegand…·Samuel H. Sternberg
This study shows that temperate phages enhance bacterial fitness by remodeling flagella via RNA-guided transcription factors, improving motility and immune evasion.
Florian T. Hoffmann, Tanner Wiegand, Adriana I. Palmieri…·Samuel H. Sternberg
The paper identifies a novel RNA-guided transcription mechanism using dCas12f and σE factors in E. coli, enabling gene activation without traditional promoter motifs.
Renjian Xiao, Florian T. Hoffmann, Dan Xie…·Leifu Chang
This study determines cryo-EM structures of the dCas12f-σE-RNAP complex to reveal a novel RNA-guided transcription mechanism in bacteria.
Tanner Wiegand, Florian T. Hoffmann, Matt W.G. Walker…·Samuel H. Sternberg
The paper identifies TnpB-like nuclease-dead repressors (TldR) as RNA-guided transcription factors that emerged through domestication of transposon-encoded TnpB nucleases, pre-dating CRISPR-Cas systems.
Chance Meers, Hoang Le, Sanjana R. Pesari…·Samuel H. Sternberg
This study shows that transposon-encoded nucleases use guide RNAs to bias transposon inheritance by cleaving donor joints formed during transposition.