Jannie Marie Bülow Sand

Type VI collagen is proportionally lower around airways and blood vessels in idiopathic pulmonary fibrosis

The paper shows that in IPF lungs, COL6 gene expression is higher but protein levels and synthesis around airways and vessels are lower, suggesting disrupted matrix organization and fibroblast persistence.

Circulating biomarkers reflecting type III, IV and VI collagen remodeling are present in lung tissue of patients with pulmonary fibrosis and non-fibrotic controls

This study shows that collagen remodeling biomarkers, found in circulation, are present in lung tissue of pulmonary fibrosis patients and non-fibrotic controls, with distinct spatial distributions.

Extracellular Matrix-Induced Genes May Reduce Response to Rapamycin in LAM

This study identifies extracellular matrix genes that reduce rapamycin response in LAM cells and suggests repurposed inhibitors as potential therapies.

It takes two: Aberrant repair and low-grade inflammation characterizes bronchiolitis obliterans syndrome after lung transplantation in serum proteomic analysis

This study identifies protein expression differences in serum associated with fibrosis and inflammation in bronchiolitis obliterans syndrome after lung transplantation.