Safi Dokmak

Distinct Progression Paths Underlie the Diversity of Pancreatic Papillary Cystic Neoplasms

The paper identifies distinct progression paths in pancreatic papillary cystic neoplasms using integrated transcriptomics and histology, enabling phenotype-specific prediction of high-grade dysplasia.

Malaria parasites undergo a rapid and extensive metamorphosis after invasion of the host erythrocyte

This study shows that Plasmodium falciparum undergoes a rapid metamorphosis after invading erythrocytes, mediated by PV6, which aids parasite survival by altering erythrocyte surface area.

Proteostasis and metabolic dysfunction in a distinct subset of storage-induced senescent erythrocytes targeted for clearance

This study identifies molecular and cellular changes in storage-induced senescent erythrocytes (SMEs) that lead to their clearance, showing altered metabolism, proteostasis, and membrane properties.