High throughput screening identifies SOX2 as a Super Pioneer Factor that inhibits DNA methylation maintenance at its binding sites
Ludovica Vanzan, Hadrien Soldati, Victor Ythier, Santosh Kumar Anand, Simon M. G. Braun, Nicole Jane Francis, Rabih Murr
The paper identifies SOX2 as a super pioneer factor that inhibits DNA methylation maintenance at its binding sites through passive demethylation during replication.
Nature Communications · Jun 7, 2021Peer-reviewedGenetics