Gustavo A. Ruiz Buendía

Multiomic profiling of human and canine soft-tissue sarcomas reveals extensive molecular homology across species and identifies clinically relevant subgroups

This study compares multiomic profiles of human and canine soft-tissue sarcomas, revealing molecular similarities and identifying clinically relevant subgroups.

Age- and Virus-Specific Signatures of In Vitro Reconstituted Human Airway Epithelia in the Presence and Absence of Respiratory Viral Infections

This study compares age-specific immune responses to respiratory viruses in human airway epithelia, finding distinct SARS-CoV-2 signatures in children that may explain milder disease.

Expanded CAG/CTG Repeats Resist Gene Silencing Mediated by Targeted Epigenome Editing

The paper develops a system to study how expanded CAG/CTG repeats affect gene silencing via epigenome editing and finds that repeats reduce silencing effectiveness.

Three-dimensional chromatin interactions remain stable upon CAG/CTG repeat expansion

This study investigates whether CAG/CTG repeat expansion alters chromatin folding using 4C sequencing and finds that chromatin contacts remain stable despite repeat expansion.