Benedikt Gille

A conserved transcriptomic model defines metabolic resilience and vulnerability in obesity

The paper constructs a transcriptomic BMI model to identify molecular differences between metabolically healthy and unhealthy obesity in humans and validates it in mice.

Sodium butyrate is incorporated into central metabolism in fly head while inducing oxygen consumption increase

This study shows that butyrate is metabolized into the TCA cycle in fly heads and increases oxygen consumption without affecting proteome or acetylome.

Longevity interventions in Titan mice attenuate frailty and senescence accumulation

This study shows that dietary intervention and senolytic drug treatment reduce frailty and senescence in Titan mice, making them a useful model for studying longevity interventions.