Shahaf Peleg

The paper constructs a transcriptomic BMI model to identify molecular differences between metabolically healthy and unhealthy obesity in humans and validates it in mice.

This study shows that Reserpine extends lifespan in Drosophila but reduces heat-stress resilience, revealing a trade-off between longevity and stress response.

This study shows that Chameau (HBO1) enhances starvation resilience in Drosophila melanogaster at lower temperatures, but its role diminishes at higher temperatures.

This study shows that butyrate is metabolized into the TCA cycle in fly heads and increases oxygen consumption without affecting proteome or acetylome.

This study shows that dietary intervention and senolytic drug treatment reduce frailty and senescence in Titan mice, making them a useful model for studying longevity interventions.