Tunable Tau Expression in C. elegans Neurons Reveals that Early-AD Tau Phosphorylation Selectively Impacts Behavior and Mitochondrial Quality Control
Thomas Carroll, Dylan Pfendler, Haya Alhaj Arhayem…·K. Nehrke
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Research Institute for Farm Animal Biology (FBN)ORCID 0000-0002-6138-2706Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
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Thomas Carroll, Dylan Pfendler, Haya Alhaj Arhayem…·K. Nehrke
Annika Müller-Eigner, Benedikt Gille, Frederik Dethloff…·Shahaf Peleg
This study shows that butyrate is metabolized into the TCA cycle in fly heads and increases oxygen consumption without affecting proteome or acetylome.
Benedikt Gille, Annika Müller-Eigner, Shari Gottschalk…·Shahaf Peleg
This study shows that dietary intervention and senolytic drug treatment reduce frailty and senescence in Titan mice, making them a useful model for studying longevity interventions.
Shon A. Koren, Nada Ahmed Selim, Lizbeth De la Rosa…·Andrew P. Wojtovich
The paper maps ROS dynamics in mitochondrial microdomains using all-optical methods to study spatiotemporal H2O2 diffusion and its effects on mitochondrial behavior.