Étienne Kornobis

This study shows SARS-CoV-2 ORF9b uses TOMM70 to avoid proteasomal degradation, reduces inflammation, and is not essential for viral replication or lung pathology.

This study evaluates monoclonal antibodies RVC20 and RVC58 for treating symptomatic rabies in mice, showing that intravenous and intramuscular administration can clear viral infection and improve survival, with RVC58 achieving 80% survival.

The paper identifies stress-responsive Mycobacterium tuberculosis subpopulations that influence macrophage polarization and shows targeting GroEL2 can limit inflammation.

The paper analyzes telomere length distributions in 100 Saccharomyces cerevisiae strains, revealing diversity influenced by ploidy, subtelomere structure, and Y element content.

The paper describes a method to simultaneously extract high-quality RNA and proteins from the same mosquito samples, enabling both RNA-Seq and LC-MS proteomic analyses.

This study shows that mutant CHCHD10 causes mitochondrial dysfunction and cardiomyopathy by disrupting cytochrome c oxidation and activating retrograde signaling.

This study investigates how a SOD-deficient bacterial pathogen adapts to superoxide stress through metabolic pathways rather than enzymatic defenses.

This study shows that SARS-CoV-2 infects and persists in hamster brainstem, causing neurodegenerative and immunometabolic changes linked to neuropsychiatric and cognitive symptoms.

This study shows that the SARS-CoV-2 E protein's PDZ-binding motif enhances virulence by disrupting epithelial barriers and inflammation, but not neuroinvasion.

This study investigates the incomplete lytic cycle of hankyphage, a Bacteroides bacteriophage, revealing defective virion formation and incomplete DNA packaging.

This study identifies how DHX37 variants disrupt RNA processing and gene expression in Sertoli-like cells, leading to 46,XY sex reversal.

This paper presents 142 high-quality yeast genomes to improve pangenome understanding, identifying structural variants and complex genomic regions.

BioConvert simplifies life science data format conversion by aggregating tools and providing a unified interface, supporting 50 formats and 100 conversions.

This study investigates SARS-CoV-2 infection in the olfactory system, showing viral persistence and inflammation linked to prolonged loss of smell in COVID-19 patients.

This study uses hiPSCs from DMD patients to model myogenesis and identifies early disease phenotypes before skeletal muscle commitment.

The paper identifies HP1γ's RNA binding activity in transcribed genes and shows it enhances splicing fidelity by tethering pre-mRNA to chromatin through intronic repeats.

The paper investigates how DNA methylation affects alternative splicing in tumors, finding that meDNA influences splicing patterns and is linked to cancer progression.

The paper shows that dieldrin activates endogenous retroviruses in MS by triggering multiple signaling pathways and altering transcriptional regulation.