Marcus Thelen

GRK-dependent ACKR3 endocytosis and chemokine scavenging is independent of receptor phosphorylation and beta-arrestin

This study shows that GRKs are essential for ACKR3 endocytosis and chemokine scavenging, while β-arrestins and receptor phosphorylation are not required.

ACKR5/GPR182 is a scavenger receptor for the atypical chemokine CXCL17, GPR15L and various endogenous peptides

This study identifies GPR182/ACKR5 as a scavenger receptor for CXCL17, GPR15L, and endogenous peptides, revealing distinct binding modes and expanding its ligand repertoire beyond classical chemokines.

Transformer-based spatial-temporal detection of apoptotic cell death in live-cell imaging.

This paper introduces ADeS, a deep learning system for detecting apoptosis in live-cell imaging with high accuracy and robustness across diverse conditions.

Semi-supervised machine learning facilitates cell colocalization and tracking in intravital microscopy

This paper introduces a semi-supervised machine learning method to improve cell colocalization and tracking in 2P-IVM videos by incorporating user-drawn lines to guide the model.