Caroline Tapparel

Ex vivo human airway epithelia modelling reveals specific alterations in lung and hematopoietic stem cell transplant recipients

The paper examines ex vivo airway epithelial cultures from transplant recipients to identify epithelial changes associated with bronchiolitis obliterans syndrome.

Human airway organoids as a high-throughput screening platform for antiviral natural products discovery

This study uses human airway organoids to screen 764 natural plant extracts for antiviral activity against RSV, identifying 45 active compounds with distinct mechanisms.

Single-cell RNA sequencing identifies progenitor dysfunction, inflammation and premature aging in ex vivo airway epithelium-derived from transplant recipients

The paper uses single-cell RNA sequencing to identify epithelial dysfunction, inflammation, and premature aging in airway epithelium from transplant recipients, linking these features to bronchiolitis obliterans syndrome.

Generation of apical-out nasal organoids to facilitate viral infection and drug screening

This paper describes a method to generate apical-out nasal organoids from nasal epithelial cells, which can be used for studying viral infections and drug responses.

A novel anti-influenza combined therapy assessed by single cell RNA-sequencing

This study evaluates a combined anti-influenza therapy using single cell RNA sequencing to show its effectiveness in inhibiting viral replication across different epithelial cell types.