Reza Rahimian

This study identifies widespread gene expression changes in the neurovascular unit of female depressed suicides with childhood abuse histories, highlighting key regulators like KLF2 and KLF4.

This study identifies differential chromatin architecture and risk variants in specific brain cell types associated with major depressive disorder.

The paper investigates BMAL1 expression in human and mouse microglia using multiple methods and finds minimal or absent expression, with epigenetic factors likely suppressing it.

The paper investigates how childhood abuse affects microglial markers and perineuronal nets in the ventromedial prefrontal cortex of individuals who died by suicide.

The paper uses spatial transcriptomics and FISH to analyze adult hippocampal neurogenesis in the human dentate gyrus across ages, finding few neural stem cell markers but significant DCX expression with mixed inhibitory and excitatory phenotypes.

This study identifies proteomic changes in the human male olfactory bulb associated with depression, highlighting astrocytic dysfunction and species-specific differences in mouse models.

This study examines CS disaccharide sulfation patterns in human and mouse brains, finding regional and species-specific differences and showing ELS does not affect PNN labeling patterns.

The paper introduces a method to isolate intact microvessels from frozen tissue and uses multi-omics to characterize the neurovascular unit.

This study shows that early-life stress alters microglial transcriptome and function in mice, affecting phagocytic capacity and gene expression in adulthood.