Sunaina Surana

The neuropathy-causing GARS1{triangleup}ETAQ mutation drives pathology in subsets of motor and sensory neurons in mice

This study shows that the Gars{Delta}ETAQ mutation in mice causes specific peripheral nerve pathology in motor and sensory neurons, affecting multiple functions and providing a model for CMT2D research.

Boosting BDNF in muscle rescues impaired axonal transport in a mouse model of DI-CMTC peripheral neuropathy

Botulinum neurotoxin A modulates the axonal release of pathological tau in hippocampal neurons

This study investigates how botulinum neurotoxin A affects the release of mutant tau in hippocampal neurons, showing it blocks mutant tau release by modulating SNAP25.

BDNF-dependent modulation of axonal transport is selectively impaired in ALS

This study shows that BDNF-dependent axonal transport is selectively impaired in fast motor neurons of ALS mice, contributing to disease pathology.

Pathophysiology of Dyt1 dystonia is mediated by spinal cord dysfunction

This study shows that spinal cord dysfunction contributes to DYT1 dystonia by creating mouse models with dystonia-like symptoms.