Author

Marc Y. Fink

Georgetown UniversityORCID 0000-0002-3550-3455Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:cell signaling & trafficking· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1 Approach:wet-lab / biochemical assay· 1

Frequent Co-Authors

Steven M. SingeriD· 2 shared Aline Sardinha-SilvaiD· 1 shared Beth Gregg· 1 shared Camila H. CoelhoiD· 1 shared Eleanor G Miskovsky· 1 shared Eliza V.C. Alves‐FerreiraiD· 1 shared Erick T. TjhiniD· 1 shared Fabrício Marcus Silva OliveiraiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersImmunology

Steven M. SingerORCID

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2 papers

Recent·Most cited

Giardia intestinalis reshapes mucosal immunity toward a Type 2 response that attenuates inflammatory bowel-like diseases

Aline Sardinha-Silva, Pedro Henrique Gazzinelli-Guimarães, Oluwaremilekun Grace Ajakaye, Fabrício Marcus Silva Oliveira, Tiago Rodrigues Ferreira, Eliza V.C. Alves‐Ferreira, Erick T. Tjhin, Beth Gregg, Marc Y. Fink, Camila H. Coelho, Steven M. Singer, Michael E. Grigg

This study shows Giardia intestinalis induces a Type 2 immune response that reduces inflammation in the gut, protecting against inflammatory bowel-like diseases.

Nature Microbiology · Jul 8, 2025Peer-reviewedImmunology

Giardia Increases Macrophage Production of the Anti-Inflammatory Cytokine Interleukin-10 in Response to Lipopolysaccharide via Macrophage Galactose Binding Lectin (MGL1)

Vanessa V Angelova, Rita Taye Kosile, Matthew Darmadi, Eleanor G Miskovsky, Marc Y. Fink, Samantha Menegas, Haley Wexelblatt, Steven M. Singer

This study shows Giardia increases macrophage IL-10 production in response to LPS via MGL1, suggesting a mechanism for its anti-inflammatory effects.

ImmunoHorizons · May 30, 2025Peer-reviewedImmunology