Author

Delphine Bonhomme

InsermORCID 0000-0002-3590-534XUnclaimed ORCID profile · follow to get notified of new preprints

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Approach:comparative / phylogenetic analysis· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

Alexis CorneciD· 1 shared Anny WangiD· 1 shared Aude G. BernheimiD· 1 shared Axel BenchetritiD· 1 shared Benjamin R. MorehouseiD· 1 shared Charlie BoriesiD· 1 shared Eirene Marie Q. EdnacotiD· 1 shared Enzo Z. PoirieriD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperImmunology

Alexis CornecORCID

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1 paper

Recent·Most cited

A human homolog of SIR2 antiphage proteins mediates immunity via the TLR pathway

Delphine Bonhomme, Hugo Vaysset, Eirene Marie Q. Ednacot, Vasco Rodrigues, Yazan Salloum, Jean Cury, Anny Wang, Axel Benchetrit, Pierre Affaticati, Veronica Hernandez Trejo, Paul Vittot, Charlie Bories, Alexis Cornec, Jean‐Pierre Levraud, Pedro P. Hernández, , Enzo Z. Poirier

The paper identifies SIRanc, a human homolog of bacterial antiphage SIR2 proteins, and shows it mediates innate immunity via the TLR pathway by degrading NAD+.

Science · Jul 24, 2025Peer-reviewedImmunology