Author

Yuting J. Tan

Vanderbilt UniversityORCID 0000-0002-3605-1307Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Genetic & Genomic Medicine· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 2 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Approach:contrastive learning· 1 Research Focus:database / resource· 1

Frequent Co-Authors

Anshul TiwariiD· 2 shared Bingshan LiiD· 2 shared Rui CheniD· 2 shared Xue Yun ZhongiD· 2 shared Aarooran Sivakumaran DurairajiD· 1 shared Abigail J. ZuckermaniD· 1 shared Aisling M. ChaneyiD· 1 shared Bradley MaliniD· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersBioinformatics

Anshul TiwariORCID

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Author profile →

3 papers

Recent·Most cited

scCotag: Diagonal integration of single-cell multi-omics data via prior-informed co-optimal transport and regularized barycentric mapping

Yang Li, Yuting J. Tan, Rui Chen, Xin Zhou, You Chen, Yuankai Huo, Xingyi Guo, Anshul Tiwari, Zhexing Wen, Xue Yun Zhong, Bradley Malin, Bingshan Li, Zhijun Yin

scCotag improves single-cell multi-omics integration by using co-optimal transport and regularized barycentric mapping, outperforming existing methods in alignment and embedding accuracy.

bioRxiv · Dec 15, 2025 · PreprintBioinformatics

A genetics-guided integrative framework for drug repurposing: identifying antihypertensive drug telmisartan for type 2 diabetes

Xue Yun Zhong, Qiang Wei, Anshul Tiwari, Quan Wang, Yuting J. Tan, Rui Chen, Yan Yan, Nancy Jean Cox, Bingshan Li

This study develops a genetics-informed framework to repurpose drugs for type 2 diabetes, identifying telmisartan as a potential treatment based on GWAS data and EHR validation.

medRxiv · Mar 22, 2025 · PreprintGenetic & Genomic Medicine

TREM1 disrupts myeloid bioenergetics and cognitive function in aging and Alzheimer disease models

Edward N. Wilson, Congcong Wang, Michelle S. Swarovski, Kristy A. Zera, Hannah E. Ennerfelt, Qian Wang, Aisling M. Chaney, Esha Gauba, Javier A. Ramos Benitez, Yann Le Guen, Paras Singh Minhas, Maharshi Panchal, Yuting J. Tan, Eran Blacher, Chinyere Agbaegbu Iweka, , Katrin I. Andreasson

This study shows that TREM1 deficiency prevents age-related myeloid metabolic changes and cognitive decline in Alzheimer's disease models.

bioRxiv · Mar 5, 2024 · PreprintNeuroscience