Author

Paras Singh Minhas

Stanford MedicineORCID 0000-0002-7741-3327Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 4

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Research Focus:differential expression· 4 Organism:human· 3 Organism:mouse· 3 Assay:proteomics· 3 Approach:statistical model· 3 Research Focus:benchmarking· 2 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2

Frequent Co-Authors

Katrin I. AndreassoniD· 4 shared Edward N. WilsoniD· 3 shared Frank M. LongoiD· 3 shared Qian WangiD· 3 shared Aarooran Sivakumaran DurairajiD· 2 shared Abigail J. ZuckermaniD· 2 shared Amira Latif‐HernandeziD· 2 shared Geidy E. SerranoiD· 2 shared

Activity by Year

2019-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 44 mutual co-author links

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Focal author (center)Selected co-authorORCID co-authorUnlinked name

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4 shared papersNeuroscience

Katrin I. AndreassonORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Restoring hippocampal glucose metabolism rescues cognition across Alzheimer's disease pathologies

Paras Singh Minhas, Jeffrey R. Jones, Amira Latif‐Hernandez, Yuki Sugiura, Aarooran Sivakumaran Durairaj, Qian Wang, Siddhita D. Mhatre, Takeshi Uenaka, Joshua D. Crapser, Travis E. Conley, Hannah E. Ennerfelt, Yoo Jin Jung, Ling Liu, Praveena Prasad, Brenita C. Jenkins, , Katrin I. Andreasson

This study shows that inhibiting IDO1 restores hippocampal glucose metabolism and rescues cognition in Alzheimer's disease models.

Science · Aug 22, 2024Peer-reviewedNeuroscience

A TrkB and TrkC partial agonist restores deficits in synaptic function and promotes activity-dependent synaptic and microglial transcriptomic changes in a late-stage Alzheimer's mouse model

Amira Latif‐Hernandez, Tao Yang, Robert R. Butler, Patricia Morán Losada, Paras Singh Minhas, Halle White, Kevin C Tran, Harry Liu, Danielle A. Simmons, Vanessa F. Langness, Katrin I. Andreasson, Tony Wyss‐Coray, Frank M. Longo

BD10-2, a TrkB/C partial agonist, improves memory and LTP deficits in Alzheimer's mice by modulating synaptic signaling and microglial transcriptomic changes.

Alzheimer s & Dementia · May 23, 2024Peer-reviewedNeuroscience

TREM1 disrupts myeloid bioenergetics and cognitive function in aging and Alzheimer disease models

Edward N. Wilson, Congcong Wang, Michelle S. Swarovski, Kristy A. Zera, Hannah E. Ennerfelt, Qian Wang, Aisling M. Chaney, Esha Gauba, Javier A. Ramos Benitez, Yann Le Guen, Paras Singh Minhas, Maharshi Panchal, Yuting J. Tan, Eran Blacher, Chinyere Agbaegbu Iweka, , Katrin I. Andreasson

This study shows that TREM1 deficiency prevents age-related myeloid metabolic changes and cognitive decline in Alzheimer's disease models.

bioRxiv · Mar 5, 2024 · PreprintNeuroscience

CSF sTREM2 correlates with CSF tau in advancing Parkinson’s disease

Edward N. Wilson, Michelle S. Swarovski, Patricia Linortner, Marian Shahid, Abigail J. Zuckerman, Qian Wang, Divya Channappa, Paras Singh Minhas, Siddhita D. Mhatre, Edward D. Plowey, Joseph F. Quinn, Cyrus P. Zabetian, Lü Tian, Frank M. Longo, Brenna Cholerton, , Katrin I. Andreasson

The paper examines the correlation between CSF sTREM2 and CSF tau levels in Parkinson’s disease and finds that sTREM2 is elevated in PD subgroups with abnormal tau but not Aβ.

bioRxiv · Jun 30, 2019 · PreprintNeuroscience