Sara Medina‐Suárez

This study shows Msc1 in yeast localizes to nucleus-vacuole junctions and excludes NPCs, maintaining NPC homeostasis during quiescence preparation.

This study shows that the nuclear envelope protein Msc1 and the ESCRT-III complex are essential for DNA double-strand break repair during late mitosis and G2/M phases.

The paper identifies Msc1 as a nuclear envelope protein that enhances DNA repair in late mitosis by supporting homologous recombination.

This study shows that Top2 deficiency in yeast causes a structural shift in chromosomes after replication, leading to segregation issues without triggering G2/M checkpoints.