Bradford Hull

This study identifies experimental variables affecting stress response outcomes in C. elegans aging research and proposes standardized guidelines to improve reproducibility.

This paper investigates how 3HAA and haao-1 inhibition affect C. elegans immune function and aging, finding that 3HAA improves immune function and acts as an antimicrobial against gram-negative bacteria.

The paper shows that inhibiting haao-1 in C. elegans enhances oxidative stress resistance by activating the Nrf2/SKN-1 pathway through a hormetic redox mechanism.