Author

Silvia Parolo

Istituto di Genetica MolecolareORCID 0000-0002-3671-5353Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Abdellatif BaaliiD· 1 shared Alberto PiazzaiD· 1 shared Alessandro AchilliiD· 1 shared Alessandro RaveaneiD· 1 shared Alexander I. WardiD· 1 shared Andrea AngiusiD· 1 shared Anna Maria Di BlasioiD· 1 shared Anna OlivieriiD· 1 shared

Activity by Year

2019-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperGenomics

Abdellatif BaaliORCID

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2 papers

Recent·Most cited

Critical role for the TGF-β1/mTORC1 signalling axis in defining the transcriptional identity of CTHRC1+ pathologic fibroblasts

Jo-Anne A M Wilson, Rachel Walters, Greg Contento, Madeleine Rossanese, Delphine Guillotin, Alexander I. Ward, Robert E. Hynds, Mariam Jamal‐Hanjani, Naftali Kaminski, Silvia Parolo, Manuela Platé, Rachel Clare Chambers

This study shows that the TGF-β1/mTORC1 signalling axis regulates the transcriptional identity of CTHRC1+ fibroblasts in IPF, supporting mTORC1 as a therapeutic target.

Science Advances · Sep 2, 2026Peer-reviewedCell Biology

Population structure of modern-day Italians reveals patterns of ancient and archaic ancestries in Southern Europe

Alessandro Raveane, Serena Aneli, Francesco Montinaro, Georgios I. Athanasiadis, Simona Barlera, Giovanni Birolo, Giorgio Battista Boncoraglio, Anna Maria Di Blasio, Cornelia Di Gaetano, Luca Pagani, Silvia Parolo, Peristera Paschou, Alberto Piazza, George Stamatoyannopoulos, Andrea Angius, , Cristian Capelli

The paper analyzes the genetic structure of modern-day Italians to reveal ancient and archaic ancestries shaping Southern European populations and Neanderthal DNA distribution.

Science Advances · Sep 4, 2019Peer-reviewedGenomics