Author

Paul Smith

University College LondonORCID 0000-0002-3676-5318Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Paul Smith2 papers · Columbia University

Biology Disciplines

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Biochemistry· 1 Biophysics· 1 Cancer Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:benchmarking· 1 Research Focus:cell signaling & trafficking· 1 Approach:deep learning· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

Vincenzo D’AngiolellaiD· 2 shared Alessio ButeraiD· 1 shared Ana JaniciD· 1 shared Andreas J GruberiD· 1 shared Anette E. SchragiD· 1 shared Aswin Abraham· 1 shared Beatrice Salerno· 1 shared Benedikt Mathias KessleriD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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2 shared papersCancer Biology

Vincenzo D’AngiolellaORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

A p53-dependent FBXO44-RAD18 axis limits mutagenesis by terminating translesion DNA synthesis

Alessio Butera, Sabrina Caporali, Francesco Capradossi, Paul Smith, Nino Tabagari, Nora Nikoloska, Olga M. Mayans, Ana Janic, Andreas J Gruber, Vincenzo D’Angiolella, Ivano Amelio

The paper identifies a p53-FBXO44-RAD18 axis that limits mutagenesis by terminating translesion DNA synthesis after replication stress.

bioRxiv · Jul 28, 2026 · PreprintCancer Biology

The ENIGMA-PD-WML Pipeline: A Containerized, User-Friendly Approach for Accurate, Standardized Segmentation of White Matter Lesions in Multi-Site MRI Data

Sarah Al–Bachari, Shauna Angell, Aswin Abraham, Yahya Khubrani, Paul Smith, Kimberly Meechan, R. E. Long, Sunanda Somu, Renee Mapa, Conor Owens‐Walton, Elizabeth Haddad, Sophia I. Thomopoulos, Carole H. Sudre, Ludovica Griffanti, Hosung Kim, , Hamied A. Haroon

bioRxiv · Jun 16, 2026 · PreprintNeuroscience

Validating folding energy estimates as a method for variant interpretation

Clementine Elwes, Rachel Alcraft, Harris Lister, Paul Smith, David Shorthouse, Benjamin A. Hall

This study validates folding energy estimates for variant interpretation, showing that while correlation coefficients are low, the method can improve prediction accuracy by identifying and addressing outlier residues.

bioRxiv · Nov 9, 2025 · PreprintBiophysics

Pervasive phenotypic effects of Fbxo42 controlled by regulation of PP4 phosphatase

Hongbin Yang, Paul Smith, Yingying Ma, Emily Southworth, Varun Gopala Krishna, Beatrice Salerno, J. Rowland, Domenico Grieco, Iolanda Vendrell, Román Fischer, Benedikt Mathias Kessler, Vincenzo D’Angiolella

This study identifies FBXO42 as a regulator of PP4 phosphatase activity, showing its role in controlling cellular processes through ubiquitination of PP4.

bioRxiv · May 2, 2025 · PreprintBiochemistry