Author

Tim Schäfer

Goethe University FrankfurtORCID 0000-0002-3683-8070Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:statistical model· 3 Research Focus:software / tool· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:electronic health records· 1 Approach:experimental assay· 1

Frequent Co-Authors

Christine EckeriD· 2 shared Anthi C. KrontiraiD· 1 shared Carolin MoessnangiD· 1 shared Caroline ManniD· 1 shared Catarina Raimundo· 1 shared Christian F. BeckmanniD· 1 shared Claudia DöeringiD· 1 shared Cristiana CruceanuiD· 1 shared

Activity by Year

2017-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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2 shared papersNeuroscience

Christine EckerORCID

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Author profile →

5 papers

Recent·Most cited

Chronic exposure to glucocorticoids amplifies inhibitory neuron cell fate during human neurodevelopment in organoids

Leander Dony, Anthi C. Krontira, Lea Kaspar, Ruhel Ahmad, Ilknur Safak Demirel, Małgorzata Grochowicz, Tim Schäfer, Fatema Begum, Vincenza Sportelli, Catarina Raimundo, Maik Ködel, Marta S. Labeur, Silvia Cappello, Fabian Joachim Theis, Cristiana Cruceanu, Elisabeth B. Binder

This study shows chronic glucocorticoid exposure alters lineage specification in human neural organoids by priming inhibitory neuron fate through transcription factors like PBX3.

Science Advances · Feb 14, 2025Peer-reviewedNeuroscience

Systems Neuroscience Computing in Python (SyNCoPy): A Python Package for Large-scale Analysis of Electrophysiological Data

Gregor Mönke, Tim Schäfer, Mohsen Parto-Dezfouli, Diljit Singh Kajal, Stefan Fürtinger, Joscha Tapani Schmiedt, Pascal Fries

SyNCoPy is a Python package for analyzing large-scale electrophysiological data, offering time, frequency, and connectivity analyses with parallel processing and interoperability.

Frontiers in Neuroinformatics · Nov 20, 2024Peer-reviewedNeuroscience

Excitatory/inhibitory imbalance in autism: the role of glutamate and GABA gene-sets in symptoms and cortical brain structure

Viola Hollestein, Geert Poelmans, Natalie J. Forde, Christian F. Beckmann, Christine Ecker, Caroline Mann, Tim Schäfer, Carolin Moessnang, Sarah Baumeister, Tobias Banaschewski, Thomas Bourgeron, Eva Loth, Flavio Dell’Acqua, Declan Murphy, Nicolaas A.J. Puts, , Jilly Naaijen

The paper investigates the relationship between glutamate and GABA gene-sets, autism symptoms, and cortical thickness using data from the EU-AIMS LEAP cohort.

Translational Psychiatry · Jan 21, 2023Peer-reviewedNeuroscience

fsbrain: an R package for the visualization ofstructural neuroimaging data

Tim Schäfer, Christine Ecker

fsbrain is an R package for visualizing structural neuroimaging data, offering 3D visualization, customization, and publication-quality outputs.

bioRxiv · Sep 18, 2020 · PreprintNeuroscience

Bioinformatics analysis quantifies neighborhood preferences of cancer cells in Hodgkin lymphoma.

Jennifer Scheidel, Hendrik Schaefer, Jöerg Ackermann, Marie Hebel, Tim Schäfer, Claudia Döering, Sylvia Hartmann, Martin‐Leo Hansmann, Ina Koch

The paper quantifies spatial neighborhood preferences of cancer cells in Hodgkin lymphoma using whole slide images and statistical analysis.

bioRxiv · Dec 4, 2017 · PreprintBioinformatics