Author

Shane A. Fiorenza

University of ZagrebORCID 0000-0002-3844-2352Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:statistical model· 4 Research Focus:cell signaling & trafficking· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:database / resource· 1 Organism:yeast· 1

Frequent Co-Authors

Meredith D. BettertoniD· 2 shared Nenad PaviniD· 2 shared Daniel G. SteckhahniD· 1 shared Elena DoriaiD· 1 shared Ellinor TaiiD· 1 shared Geert J.P.L. KopsiD· 1 shared Iva M. TolićiD· 1 shared Jakia Jannat KeyaiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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2 shared papersBiophysics

Meredith D. BettertonORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Shepherding by biased diffusion organizes diffusible proteins on microtubules

Leila Farhadi, Shane A. Fiorenza, Sithara S. Wijeratne, Κωνσταντίνος Νάκος, Yang Yue, Morgan L. Pimm, Jakia Jannat Keya, Kristen J. Verhey, Radhika Subramanian, Meredith D. Betterton

The paper demonstrates that motors can shepherd diffusive proteins on microtubules through biased diffusion, revealing a mechanism for spatial patterning without direct binding.

Nature Physics · Oct 30, 2026Peer-reviewedBiophysics

Coordinated control of both microtubule ends regulates mitotic spindle length

Shane A. Fiorenza, Sheba Cheeran, Elena Doria, Iva M. Tolić, Patrick Meraldi, Nenad Pavin

This study resolves a paradox in spindle length control by showing that coordinated regulation at both microtubule ends allows spindle length and poleward flux to vary independently.

bioRxiv · Feb 9, 2026 · PreprintBiophysics

Distinct aneuploid karyotypes are universally selected for across cancers

Lucija Tomašić, Shane A. Fiorenza, Thomas W van Ravesteyn, Geert J.P.L. Kops, Nenad Pavin

The paper identifies binary karyotypes as universally selected in cancers and yeast, showing lower TP53 mutation rates and increased fitness compared to other aneuploid karyotypes.

bioRxiv · Jul 25, 2025 · PreprintCancer Biology

PRC1 resists microtubule sliding in two distinct resistive modes due to variations in the separation between overlapping microtubules

Daniel G. Steckhahn, Shane A. Fiorenza, Ellinor Tai, Scott T. Forth, Peter R. Kramer, Meredith D. Betterton

The paper develops a computational model of PRC1 crosslinked microtubule pairs to show that braking and coasting modes depend on lateral separation, with braking reducing sliding speed more effectively.

Molecular Biology of the Cell · Jul 2, 2025Peer-reviewedBiophysics