Author

Laureline Bétemps

Centre National de la Recherche Scientifique

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:human· 1 Research Focus:variant calling· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Arnaud F. KleiniD· 1 shared Bruno Dumas· 1 shared David Viterbo· 1 shared Denis FurlingiD· 1 shared Geneviève GourdoniD· 1 shared Guy‐Franck RichardiD· 1 shared Laurence MaiD· 1 shared Lucie PoggiiD· 1 shared

Activity by Year

2023-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperGenomics

Arnaud F. KleinORCID

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1 paper

Recent·Most cited

TALEN-induced contraction of CTG trinucleotide repeats in myotonic dystrophy type 1 cells

Laureline Bétemps, Stéphane Descorps-Declère, Olivia Frenoy, Lucie Poggi, Valentine Mosbach, Stéphanie Tomé, David Viterbo, Arnaud F. Klein, Laurence Ma, Sonia Lameiras, Thomas Cokelaer, Marc Monot, Bruno Dumas, Geneviève Gourdon, Denis Furling, Guy‐Franck Richard

This study uses TALENs to contract CTG repeats in DM1 cells, achieving 68% contraction with a recoded TALEN, while SaCas9 failed, and identifies potential off-target effects.

bioRxiv · Oct 14, 2023 · PreprintGenomics