Author

Abhilash Jayaraj

Harvard UniversityORCID 0000-0002-3974-6518Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2 Biochemistry· 1 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:differential expression· 2 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Haribabu ArthanariiD· 4 shared Hyuk‐Soo SeoiD· 3 shared Chelsea BraithwaiteiD· 2 shared Luke SebastianiD· 2 shared Sirano Dhe‐PaganoniD· 2 shared Abhishek Kumar· 1 shared Aditya KumariD· 1 shared AkshatKumar NigamiD· 1 shared

Activity by Year

2023-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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4 shared papersMolecular Biology

Haribabu ArthanariORCID

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4 papers

Recent·Most cited

BiochemistrybioRxivPreprintOct 28, 2026

ssDNA hand-off from RPA to Polθ drives microhomology-mediated end-joining

Martha Longley, Hyunjee Lee, Owen Eby…·Johannes Walter

The paper reveals that RPA activates TMEJ by facilitating ssDNA hand-off to Polθ, which initiates microhomology search for DNA repair.

DOI 10.64898/2026.10.26.762034

experimental assay

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Molecular BiologyStructurePeer-reviewedOct 17, 2024

Structural Insights into the DNA-Binding Mechanism of BCL11A: The Integral Role of ZnF6

Thibault Viennet, Maolu Yin, Abhilash Jayaraj…·Haribabu Arthanari

This study investigates the DNA-binding mechanism of BCL11A, revealing the role of ZnF6 in repression of {gamma}-globin gene expression and its implications for therapeutic design.

6 citations

humanDNA methylation

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Molecular BiologybioRxivPreprintApr 10, 2024

Ergothioneine boosts mitochondrial respiration and exercise performance via direct activation of MPST

Hans‐Georg Sprenger, Melanie J. Mittenbühler, Yizhi Sun…·Bruce M. Spiegelman

This study identifies MPST as the direct target of EGT, showing it enhances mitochondrial respiration and exercise performance in mice.

7 citations

mouseproteomics

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BioinformaticsbioRxivPreprintApr 25, 2023

AI-Enhanced Adaptive Virtual Screening Platform Enabling Exploration of 69 Billion Molecules Discovers Structurally Validated FSP1 Inhibitors

Domiziana Cecchini, AkshatKumar Nigam, Ming Tang…·Christoph Gorgulla

AdaptiveFlow enables large-scale virtual screening of 69 billion molecules to discover validated FSP1 inhibitors, improving efficiency and scalability in drug discovery.

24 citations

experimental assaydrug response / drug discovery

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