Paul Francis Harrison

This study shows ADAR1p150 suppresses immunogenicity from tonic type I IFN-induced transcripts through editing-dependent and -independent mechanisms.

The paper compares alternative polyadenylation in primary human myoblasts and C2C12 cells during differentiation, finding less alternative polyadenylation in human cells.

langevitour provides interactive animated 2D projections of high-dimensional data using Langevin Dynamics, offering smoother visualization than UMAP for scRNA-Seq data.

The paper introduces a method to estimate splice-site strength and uses GWAS to identify genomic factors influencing splicing variation in Arabidopsis thaliana.

Topconfects ranks differentially expressed genes by confident log fold change effect sizes, improving biological interpretation over p-value-based rankings.

The paper identifies GLD-2 mediated cytoplasmic polyadenylation targets in C. elegans and shows CCF-1 as the major deadenylase for maternal mRNA silencing.