Author

Zing Tsung‐Yeh Tsai

University of MichiganORCID 0000-0002-4006-1559Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:statistical model· 4 Research Focus:differential expression· 3 Research Focus:gene regulatory network inference· 3 Assay:bulk RNA-seq· 2 Assay:ChIP-seq· 2 Assay:DNA methylation· 2 Organism:human· 2 Approach:experimental assay· 1

Frequent Co-Authors

Huai‐Kuang TsaiiD· 2 shared Alan P. BoyleiD· 1 shared Chee Khoon LeeiD· 1 shared Christopher Tai-Yi LeeiD· 1 shared Claudia LalancetteiD· 1 shared Dana C. DolinoyiD· 1 shared Jia‐Hsin HuangiD· 1 shared JM Goodrich· 1 shared

Activity by Year

2017-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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2 shared papersGenomics

Huai‐Kuang TsaiORCID

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5 papers

Recent·Most cited

BioinformaticsNAR Genomics and BioinformaticsPeer-reviewedFeb 6, 2020

Poly-Enrich: Count-based Methods for Gene Set Enrichment Testing with Genomic Regions

Christopher Tai-Yi Lee, Raymond G. Cavalcante, Chee Khoon Lee…·Maureen A. Sartor

Poly-Enrich improves gene set enrichment testing for genomic regions by modeling peak counts with a negative binomial model, outperforming previous methods in certain scenarios.

22 citations

ChIP-seqstatistical model

𝕏 PostBluesky

GenomicsbioRxivPreprintOct 2, 2019

Perinatal exposure to lead results in altered DNA methylation in adult mouse liver and blood: Implications for target versus surrogate tissue use in environmental epigenetics

Laurie Kathleen Svoboda, Kari E. Neier, R Cavalcante…·Dana C. Dolinoy

This study shows perinatal lead exposure causes sex-specific DNA methylation changes in adult mouse liver and blood, with some methylation sites overlapping between tissues.

4 citations

mouseDNA methylation

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GenomicsFrontiers in GeneticsPeer-reviewedNov 21, 2018

The borders of cis-regulatory DNA sequences harbor the divergent transcription factor binding motifs in the human genome

Jia‐Hsin Huang, Ryan Shun-Yuen Kwan, Zing Tsung‐Yeh Tsai…·Huai‐Kuang Tsai

3 citations

humanDNA methylation

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GenomicsMolecular Biology and EvolutionPeer-reviewedMar 9, 2018

Defining the functional significance of intergenic transcribed regions

John P. Lloyd, Zing Tsung‐Yeh Tsai, Rosalie P. Sowers…·Shin‐Han Shiu

The paper identifies intergenic transcribed regions (ITRs) in 15 flowering plant species and uses machine learning to classify them as functional or non-functional based on sequence and evolutionary features.

25 citations

plant (other)bulk RNA-seq

𝕏 PostBluesky

BioinformaticsBMC GenomicsPeer-reviewedOct 16, 2017

Comparative genomic analyses highlight the contribution of pseudogenized protein-coding genes to human lincRNAs

Wan‐Hsin Liu, Zing Tsung‐Yeh Tsai, Huai‐Kuang Tsai

This study identifies that a significant portion of human lincRNAs may originate from pseudogenized protein-coding genes through comparative genomic analysis.

18 citations

humanbulk RNA-seq

𝕏 PostBluesky