Author

Jong Seo Lee

Yale UniversityORCID 0000-0002-4009-8220Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell-cell communication· 1 Research Focus:drug response / drug discovery· 1 Research Focus:protein structure prediction· 1 Assay:proteomics· 1

Frequent Co-Authors

Alexa R. SoaresiD· 1 shared Armand SorianoiD· 1 shared Benjamin Sanders· 1 shared Caroline Fai· 1 shared Chang‐Woo LeeiD· 1 shared Clara LiaoiD· 1 shared Frank RigoiD· 1 shared Hannah J. RoiD· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperMolecular Biology

Alexa R. SoaresORCID

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2 papers

Recent·Most cited

Molecular BiologyMolecular CellPeer-reviewedSep 23, 2024

Alternative translation initiation produces synaptic organizer proteoforms with distinct localization and functions

Jong Seo Lee, Yu Sun, Alexa R. Soares…·Junjie U. Guo

The paper shows that alternative translation initiation sites produce proteoforms with distinct localization and functions, specifically in synaptic organizers like NPR and C1q-like proteins.

20 citations

mouseproteomics

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NeuroscienceJournal of Clinical InvestigationPeer-reviewedJun 29, 2023

Reduction of Nemo-like kinase increases lysosome biogenesis and ameliorates TDP-43-related neurodegeneration

Leon Tejwani, Youngseob Jung, Hiroshi Kokubu…·Janghoo Lim

This study shows that reducing Nemo-like kinase enhances lysosome biogenesis and improves TDP-43 clearance, alleviating neurodegeneration in mouse models.

17 citations

mouseexperimental assay

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