Author

Jian Guo Cui

Columbia University Irving Medical CenterORCID 0000-0002-4015-9484Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Fang LiiD· 2 shared Hanrui ZhangiD· 2 shared Xun WuiD· 2 shared Ziyi WangiD· 2 shared Ai YamamotoiD· 1 shared Ali JavaheriiD· 1 shared Annie Rozenblyum· 1 shared Antonio Hernández‐OnoiD· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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2 shared papersImmunology

Fang LiORCID

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2 papers

Recent·Most cited

Macrophage WDFY3, a protector against autoimmunity

Xun Wu, Ziyi Wang, Katherine R. Croce, Fang Li, Jian Guo Cui, Vivette Denise D’Agati, Rajesh Kumar Soni, Shareef Khalid, Danish Saleheen, Ira Tabas, Ai Yamamoto, Hanrui Zhang

This study shows WDFY3 protects against autoimmunity by enhancing macrophage efferocytosis, reducing autoantigen release, and suppressing T cell and inflammasome activation.

Nature Communications · Sep 30, 2025Peer-reviewedImmunology

Decoding the Variant-to-Function Relationship for LIPA, a Risk Locus for CAD

Fang Li, Elise D. Flynn, Philip Ha, Mazal N. Zebak, Haoxiang M. Cheng, Chenyi Xue, Jianting Shi, Xun Wu, Ziyi Wang, Yujiao Meng, Jian Guo Cui, Yizhou Zhu, Annie Rozenblyum, Jeana Chun, Antonio Hernández‐Ono, , Hanrui Zhang

The paper links LIPA risk alleles to increased monocyte/macrophage LIPA expression, which exacerbates atherosclerosis through enhanced PU.1 binding and altered macrophage function.

bioRxiv · Nov 12, 2022 · PreprintGenomics