Author

Junrong Yan

Rutgers, The State University of New JerseyORCID 0000-0002-4017-6065Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Assay:metabolomics· 1 Assay:proteomics· 1

Frequent Co-Authors

Brinda Kizhakke VallatiD· 1 shared Chen ZhangiD· 1 shared Christian S. HinrichsiD· 1 shared Francesco BertoniiD· 1 shared Giuseppe Caso· 1 shared Haowei LiiD· 1 shared Hassan Sajjad· 1 shared Hiromi SesakiiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCancer Biology

Brinda Kizhakke VallatORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

OSTM1 is a ubiquitin E3 ligase that suppresses B-cell malignancy by activating the cAMP/PKA/CREB pathway

Muhammad Usama Tariq, Namratha Sheshadri, Jianliang Shen, Jaeyong Jung, Haowei Li, Kevin Lu, Junrong Yan, Mark C. Koch, Giuseppe Caso, Hassan Sajjad, Brinda Kizhakke Vallat, Stephen Kevin Burley, Yi Sun, Tong Liu, Hong Li A, , Wei Zong

This study identifies OSTM1 as a tumor suppressor in B-cell malignancies by showing it activates the cAMP/PKA/CREB pathway through ubiquitin E3 ligase activity.

bioRxiv · Sep 24, 2026 · PreprintCancer Biology

Disruption of Mitochondrial Dynamics and Stasis Leads to Liver Injury and Tumorigenesis

Xiaowen Ma, Xiaoli Wei, Mengwei Niu, Chen Zhang, Zheyun Peng, Wanqing Liu, Junrong Yan, Xiaoyang Su, Shaolei Lu, Wei Cui, Hiromi Sesaki, Wei‐Xing Zong, Hong‐Min Ni, Wen‐Xing Ding

This study shows that disrupting mitochondrial fission (DRP1) leads to liver injury and tumorigenesis, while loss of fusion proteins has less impact, and triple knockout mice show reduced tumor development.

bioRxiv · Feb 11, 2025 · PreprintCell Biology