Author

Silvia Marina Vidal

McGill UniversityORCID 0000-0002-4069-4276Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

Anastasia NijnikiD· 2 shared Bianca Pozzebon· 2 shared Danielle MaloiD· 2 shared David LanglaisiD· 2 shared Inés ColmegnaiD· 2 shared Joo Eun Kim· 2 shared Lin Tze Tung· 2 shared Mathieu ManciniiD· 2 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersImmunology

Anastasia NijnikORCID

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3 papers

Recent·Most cited

Increased Expression and Altered Functional Activities of Immune Receptors TREM1, PD-L1, and Others on Hematopoietic Progenitor Cells in a Mouse Model of Rheumatoid Arthritis

Johanna M Toth, Roselyn R. Jiang, Lin Tze Tung, Dania Shaban, Mathieu Mancini, Bianca Pozzebon, Joo Eun Kim, Mitra Yousefi, Danielle Malo, Silvia Marina Vidal, Inés Colmegna, David Langlais, Anastasia Nijnik

This study shows that immune receptors on hematopoietic progenitor cells are upregulated in a mouse model of rheumatoid arthritis and that stimulating these receptors alters cell expansion and differentiation.

bioRxiv · Jun 12, 2026 · PreprintImmunology

Trained Immunity Affecting Dendritic Cell Differentiation and Function in Rheumatoid Arthritis

Lin Tze Tung, Roselyn R. Jiang, Bianca Pozzebon, Mathieu Mancini, Lucie Droin, Mitra Yousefi, Joo Eun Kim, Marwah Mousa, Yue Liang, Connie M. Krawczyk, Inés Colmegna, Danielle Malo, David Langlais, Silvia Marina Vidal, Anastasia Nijnik

This study shows that trained immunity affects dendritic cell differentiation and function in rheumatoid arthritis, altering their gene expression and immune responses.

bioRxiv · Feb 28, 2025 · PreprintImmunology

Computational Intractability Law Molds the Topology of Biological Networks

Ali A Atiia, Corbin Hopper, Katsumi Inoue, Silvia Marina Vidal, Jérôme Waldispühl

The paper models molecular interaction networks as computational optimization problems, showing that their mLmH topology arises as an adaptation to computational intractability.

Applied Network Science · Jun 24, 2020Peer-reviewedSystems Biology