Author
University of California, BerkeleyORCID 0000-0002-4094-4220Unclaimed ORCID profile · follow to get notified of new preprints
5 papers
Recent·Most cited
Lucy D. Brennan, Hyeong-Ku Kim, Serafin U. Colmenares…·Gary H. Karpen
This study shows HP1a promotes chromatin liquidity and drives spontaneous heterochromatin compartmentalization through interfacial tension modulation.
Serafin U. Colmenares, Shingo Tsukamoto, Collin Hickmann…·Gary H. Karpen
The paper identifies an expanded HP1a-binding motif, HACs, and shows their role in heterochromatin assembly through molecular interactions and simulations.
Marieke R. Wensveen, Aditya A. Dixit, Robin van Schendel…·Aniek Janssen
The paper shows that DSBs in facultative heterochromatin require dUtx-mediated loss of H3K27me3 for repair by promoting DSB movement outside polycomb bodies.
Leila Lin, Yuheng Huang, Jennifer McIntyre…·Yuh Chwen G. Lee
The paper investigates the evolutionary dynamics of genes involved in heterochromatin functions in Drosophila, finding they evolve faster than Polycomb-based repressive chromatin genes.
Bhavatharini Kasinathan, Serafin U. Colmenares, Hannah McConnell…·Harmit Singh Malik
The paper shows that evolutionarily dynamic ZAD-ZNF genes in Drosophila are more likely to be essential, with Nicknack being necessary for larval development despite its rapid evolution.