Author

Yue Zhang

University of UtahORCID 0000-0002-4124-4816Unclaimed ORCID profile · follow to get notified of new preprints

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Yue Zhang15 papers · Children's Hospital of Zhejiang University

Biology Disciplines

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Bioinformatics· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:deep learning· 1 Approach:experimental assay· 1 Organism:mouse· 1 Assay:protein sequence· 1

Frequent Co-Authors

Albert S. JuniD· 1 shared Austin D. BohneriD· 1 shared Balamurali Krishna AmbatiiD· 1 shared Bomin WeiiD· 1 shared Bonnie J. Archer· 1 shared Felipe PereiraiD· 1 shared Guangping GaoiD· 1 shared Hironori UeharaiD· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperGenomics

Albert S. JunORCID

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2 papers

Recent·Most cited

DeepLPI: a novel deep learning-based model for protein-ligand interaction prediction for drug repurposing

Bomin Wei, Yue Zhang, Xiang Gong

DeepLPI is a deep learning model for predicting protein-ligand interactions, outperforming existing methods on multiple datasets.

Scientific Reports · Oct 28, 2022Peer-reviewedBioinformatics

Start codon disruption with CRISPR/Cas9 prevents murine Fuchs' endothelial corneal dystrophy

Hironori Uehara, Xiaohui Zhang, Felipe Pereira, Siddharth Narendran, Susie Choi, Sai Bhuvanagiri, Jinlu Liu, Sangeetha Ravi Kumar, Austin D. Bohner, Lara S. Carroll, Bonnie J. Archer, Yue Zhang, Wei Liu, Guangping Gao, Jayakrishna Ambati, , Balamurali Krishna Ambati

This study shows that CRISPR/Cas9 gene editing in adult mice prevents vision loss in a model of Fuchs' endothelial corneal dystrophy by disrupting the start codon of the mutant COL8A2 gene.

eLife · Jun 8, 2021Peer-reviewedGenomics