Hélène Duez

Rev-erb-alpha inhibits vascular calcification by repressing osteogenic reprogramming in atherosclerosis

This study identifies Rev-erb-alpha as a repressor of vascular calcification by inhibiting osteogenic reprogramming of vascular smooth muscle cells in atherosclerosis.

Experimental and mathematical models reveal that AMPK modulates circadian clock gene expression and period through NAD+-dependent regulation of Bmal1

The paper shows that AMPK modulates circadian clock period and Bmal1 expression through NAD+-dependent mechanisms, validated by experiments and mathematical modeling.

Hepatocyte ERα orchestrates sex-specific liver adaptation to fasting and feeding states

This study shows hepatocyte ERα regulates sex-specific liver responses to fasting and feeding, affecting gene expression and metabolic pathways differently in males and females.