Author

Anssi Pelkonen

University of Eastern FinlandORCID 0000-0002-4154-5686Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 4 Research Focus:cell type annotation· 3 Assay:electronic health records· 2 Assay:imaging· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1

Frequent Co-Authors

Tarja MalmiD· 4 shared Antonios DougalisiD· 3 shared Mireia Gómez‐BudiaiD· 3 shared Polina A. AbushikiD· 3 shared Tuomas H. RauramaaiD· 3 shared Adriana Della PietraiD· 2 shared Alejandra SierraiD· 2 shared Arto Immonen· 2 shared

Activity by Year

2023-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersNeuroscience

Tarja MalmORCID

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Author profile →

4 papers

Recent·Most cited

Microelectrode array scaled for recording human hippocampal slices

Anssi Pelkonen, Vera Lezhnyova, Tomi Ryynänen, Joose Kreutzer, Valeriia Sitnikova, Mireia Gómez‐Budia, Adriana Della Pietra, Antonios Dougalis, Jenni Kyyriäinen, Mastaneh Torkamani‐Azar, Henri Eronen, Tuomas H. Rauramaa, Arto Immonen, Ville Leinonen, Alejandra Sierra, , Tarja Malm

The paper develops a custom microelectrode array for recording extracellular action potentials and local field potentials from human hippocampal slices to study temporal lobe epilepsy.

Epilepsia Open · Mar 25, 2026Peer-reviewedNeuroscience

Multimodal approach to characterize surgically removed epileptogenic zone from patients with focal drug-resistant epilepsy: from operating room to wet lab

Jenni Kyyriäinen, Adriana Della Pietra, Mastaneh Torkamani‐Azar, Mireia Gómez‐Budia, Polina A. Abushik, Nataliia Novosolova, Henri Eronen, Omar Narvaez, Ekaterina Paasonen, Vera Lezhnyova, Anssi Pelkonen, Liudmila Saveleva, Antti Huotarinen, Ilya N Belevich, Eija Jokitalo, , Alejandra Sierra

The paper develops a protocol to characterize epileptogenic tissue using multimodal data from surgical samples, aiming to improve diagnosis and treatment of drug-resistant epilepsy.

Epilepsia Open · Dec 5, 2025Peer-reviewedNeuroscience

Early amyloid spine response and impaired synaptic transmission of pyramidal neurons in human biopsies with Alzheimer's Disease-related pathology

Antonios Dougalis, Polina A. Abushik, Anssi Pelkonen, Luca Giudice, Mireia Gómez‐Budia, Nataliia Novosolova, Nelli‐Noora Välimäki, Mohammad Rezaie, Dilyara Nurkhametova, Raisa Giniatullina, Anastasia Shakirzyanova, Akash Shivling Mali, Tuomas H. Rauramaa, Beth Stevens, Mikko Hiltunen, , Tarja Malm

This study examines how early Alzheimer's disease-related pathology affects synaptic transmission and morphology in human cortical neurons using biopsies from patients with idiopathic normal pressure hydrocephalus.

bioRxiv · Jan 7, 2025 · PreprintNeuroscience

Air-liquid interface culture of midbrain organoids improves neuronal functionality and integration of microglia

Sara Kälvälä, Polina A. Abushik, Antonios Dougalis, Tarja Malm, Anssi Pelkonen, Šárka Lehtonen

This paper develops a method to culture midbrain organoids with microglia and air-liquid interface to improve neuronal functionality and integration of microglia.

bioRxiv · Oct 10, 2023 · PreprintNeuroscience