Anastasia Shakirzyanova

This study shows that iPSC-derived neurons from FTD patients exhibit synaptic dysfunction, DNA damage, and C9-HRE-related pathologies, supporting synaptic dysfunction as a key factor in FTD.

This study examines how early Alzheimer's disease-related pathology affects synaptic transmission and morphology in human cortical neurons using biopsies from patients with idiopathic normal pressure hydrocephalus.

This study shows that activating PIEZO1 channels in microglia improves amyloid beta clearance in AD models by enhancing survival, phagocytosis, and lysosomal activity.

This study shows that incorporating microglial progenitors into human brain organoids supports neuronal maturation and synaptic activity.