Author

Jennifer Blaze

Icahn School of Medicine at Mount SinaiORCID 0000-0002-4156-0624Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:differential expression· 1 Organism:Drosophila· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Schahram AkbarianiD· 2 shared Andrew A. SprouliD· 1 shared Andrew F. TeichiD· 1 shared Atul KumariD· 1 shared Caleb J. BrowneiD· 1 shared Ellen TeiniD· 1 shared Eric J. NestleriD· 1 shared Francesca BartoliniiD· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersNeuroscience

Schahram AkbarianORCID

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2 papers

Recent·Most cited

tRNA epitranscriptomic alterations associated with opioid-induced reward-seeking and long-term opioid withdrawal

Jennifer Blaze, Caleb J. Browne, Rita Futamura, Venetia Zachariou, Eric J. Nestler, Schahram Akbarian

This study investigates how chronic morphine exposure and withdrawal alter tRNA cytosine methylation in the medial prefrontal cortex, linking these changes to reward-seeking behavior and opioid use disorder.

bioRxiv · Sep 6, 2023 · PreprintNeuroscience

NSun2 deficiency promotes tau hyperphosphorylation and neurodegeneration through epitranscriptomic regulation of miR-125b

Yoon A. Kim, Jennifer Blaze, Tristan Winters, Atul Kumar, Ellen Tein, Andrew A. Sproul, Andrew F. Teich, Francesca Bartolini, Schahram Akbarian, Gunnar Hargus, Ismael Santa‐María

This study shows NSun2 deficiency in AD leads to miR-125b dysregulation and tau hyperphosphorylation, promoting neurodegeneration through epitranscriptomic mechanisms.

bioRxiv · Jun 16, 2021 · PreprintNeuroscience