Author
Research Institute of Molecular PathologyORCID 0000-0002-4230-485XUnclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Gordana Wutz, Iain F. Davidson, Edward J. Banigan…·Jan‐Michael Peters
This study shows PDS5 proteins regulate genome architecture by stopping loop extrusion and strengthening CTCF boundaries through NIPBL dissociation from cohesin.
Lorenzo Costantino, Tiantian Ye, Kevin Boardman…·Douglas E. Koshland
The paper investigates how cohesin acetylation and ATPase activity regulate chromatin loop formation and cohesion in yeast, showing they operate through distinct mechanisms.
Lorenzo Costantino, Tsung-Han S. Hsieh, Rebecca C. Lamothe…·Douglas E. Koshland
The paper shows cohesin residency at CARs determines chromatin loop positioning in budding yeast through loop extrusion and CAR-bound cohesin stopping.
Rebecca C. Lamothe, Lorenzo Costantino, Douglas E. Koshland
The paper shows that Cdc5p kinase, regulated by cohesin, controls condensin activity to properly fold the RDN into a thin loop during mitosis in budding yeast.