Author

Rebecca C. Lamothe

University of California, BerkeleyORCID 0000-0003-4942-5950Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Genetics· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:yeast· 2 Assay:ChIP-seq· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

Douglas E. KoshlandiD· 2 shared Lorenzo CostantinoiD· 2 shared Christopher T. BrowniD· 1 shared Cindy J. CastelleiD· 1 shared Cristina N. ButterfieldiD· 1 shared Daniela S. Aliaga GoltsmaniD· 1 shared David Ward TayloriD· 1 shared Dominic T. CastanzoiD· 1 shared

Activity by Year

2020-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersGenomics

Douglas E. KoshlandORCID

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3 papers

Recent·Most cited

BiochemistryNature Structural & Molecular BiologyPeer-reviewedApr 13, 2026

Comparative characterization of Cas12f orthologs reveals mechanistic features underlying enhanced genome editing efficiency

Kaoling Guan, Rodrigo Fregoso Ocampo, Paula B. Matheus Carnevali…·David Ward Taylor

The paper compares Cas12f orthologs to identify mechanistic features that enhance genome editing efficiency in human cells.

5 citationstop 2%

humanexperimental assay

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GenomicseLifePeer-reviewedNov 10, 2020

Cohesin residency determines chromatin loop patterns

Lorenzo Costantino, Tsung-Han S. Hsieh, Rebecca C. Lamothe…·Douglas E. Koshland

The paper shows cohesin residency at CARs determines chromatin loop positioning in budding yeast through loop extrusion and CAR-bound cohesin stopping.

113 citationstop 4%

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GeneticsGenes & DevelopmentPeer-reviewedJun 1, 2020

THE SPATIAL REGULATION OF CONDENSIN ACTIVITY IN CHROMOSOME CONDENSATION

Rebecca C. Lamothe, Lorenzo Costantino, Douglas E. Koshland

The paper shows that Cdc5p kinase, regulated by cohesin, controls condensin activity to properly fold the RDN into a thin loop during mitosis in budding yeast.

16 citations

yeastexperimental assay

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