Author
University of British ColumbiaORCID 0000-0002-4275-8579Unclaimed ORCID profile · follow to get notified of new preprints
5 papers
Recent·Most cited
Arif Hussain, Kiana Tajdaran, Ramkumar Katturajan…·Konstantin Feinberg
The paper shows that denervation shifts NGF receptor signaling in corneal epithelial stem cells from TrkA-AKT to p75NTR-JNK, explaining limited rhNGF efficacy in neurotrophic keratopathy and suggesting receptor-selective modulation as a therapy.
Stefan Wendt, Ada J. Lin, Sarah N. Ebert…·Haakon B. Nygaard
This paper uses a 3D human iPSC-derived neurosphere model to study how microglia modify cellular responses to chronic amyloidosis, revealing their role in reducing neurotoxicity and regulating AD-associated gene expression.
Madeline N. Hayes, Sarah Cohen‐Gogo, Lynn Kee…·Meredith S. Irwin
This study shows DDR gene mutations enhance neuroblastoma progression and sensitivity to PARP + ATR inhibitors in zebrafish models and human cells.
Ekaterina V. Borisova, Andrew G. Newman, Marta Couce-Iglesias…·Mateusz C. Ambrozkiewicz
The paper shows that Ire1α regulates mRNA translation rates, which control the identity and polarity of upper layer cortical neurons through eIF4A1 and eEF-2.
Ashleigh Willis, Danielle Jeong, Yunlong Liu…·Freda D. Miller
The paper uses single-cell RNA-sequencing and spatial transcriptomics to study forebrain neural stem cell niches and identifies microglial ligands that enhance remyelination.