Ire1α-Regulated mRNA Translation Rate Controls the Identity and Polarity of Upper Layer Cortical Neurons
Ekaterina V. Borisova, Andrew G. Newman, Marta Couce-Iglesias, Rike Dannenberg, Theres Schaub, Bo Qin, Alexandra Rusanova, Marisa M. Brockmann, Janina Koch, Marieatou Daniels, Paul Turko, Olaf Jahn, David R. Kaplan, Marta Rosário, Takao Iwawaki, , Mateusz C. Ambrozkiewicz
The paper shows that Ire1α regulates mRNA translation rates, which control the identity and polarity of upper layer cortical neurons through eIF4A1 and eEF-2.
Nature Communications · Jun 7, 2024Peer-reviewedNeuroscience