Erica J. Hutchins

This study identifies FAM83H as a regulator linking keratin organization to Notch signaling in epidermal morphogenesis, showing its role in keratinocyte differentiation and cell-cell adhesion.

StrataChip enables dynamic study of human epidermal morphogenesis by integrating microfluidics with single-cell RNA-sequencing and imaging, revealing transcriptional and mechanical transitions during stratification.

The paper performs single-cell RNA-sequencing on developing chick trigeminal ganglion to characterize cellular diversity and identify novel transcripts.

The paper shows that gap junctions between breast cancer cells and adipocytes transfer cAMP, activating lipolysis in the tumor microenvironment to support tumor growth.

This paper adapts the CRISPR-Cas13d system for targeted gene expression knockdown in chick embryos, demonstrating effective PAX7 knockdown comparable to morpholino.

The paper identifies nSMase2 as a critical regulator of developmental EMT by inducing endocytosis to activate Wnt and BMP signaling during neural crest migration.

The paper identifies Elavl1/HuR as essential for maintaining cranial neural crest specification by stabilizing Draxin mRNA.

This study shows Draxin regulates basement membrane remodeling during cranial neural crest EMT by controlling laminin expression stages and is mediated by Snail2.