Chenqi Tao

Wnt signaling regulates passive cell competition in the retina by inducing differential cell adhesion

The paper shows that Wnt signaling, through {beta}-catenin, regulates passive cell competition in the retina by inducing a cadherin switch that segregates cells into distinct compartments.

Phospholipase Cgamma regulates lacrimal gland branching by competing with PI3K in phosphoinositide metabolism

This study shows that PLCgamma competes with PI3K in phosphoinositide metabolism to regulate lacrimal gland branching.

Chondroitin sulfates enhances the barrier function of basement membrane assembled by heparan sulfates

This study shows that chondroitin sulfates and heparan sulfates play distinct roles in the assembly and barrier function of the retinal basement membrane.

Phase transition specified by a binary code patterns the vertebrate eye cup

The paper shows that FGF and Wnt signaling gradients determine phase transitions in vertebrate eye cup development, specifying cell fates through their combinatorial code.

Deficient FGF signaling in the developing peripheral retina disrupts ciliary margin development and causes aniridia

This study shows that FGF signaling is essential for ciliary margin development in the retina, with its disruption causing aniridia by altering the boundary between the central retina and the ciliary margin.