Annelies Bogaert

The paper assesses MS-based identifications of unannotated human microproteins, finding large variation in reported proteins and PSM quality across studies.

The paper shows that N-terminal acetylation by NatC protects proteins from degradation, enhancing longevity and motility, and that UBR4-KCMF1 targets unacetylated N-terminal Met followed by hydrophobic residues.

The paper investigates N-terminal proteoforms and finds they can engage in different protein complexes compared to their canonical counterparts.

The paper investigates non-coding transcript translation in HEK293T cells, finding limited but potentially functional translation products using ribosome profiling and mass spectrometry.