Author

Steffan P. Jones

UCL Queen Square Institute of NeurologyORCID 0000-0002-4536-9982Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Assay:electronic health records· 1

Frequent Co-Authors

Dimitri Michael KullmanniD· 2 shared Gabriele LignaniiD· 2 shared Gaia ColasanteiD· 2 shared Albert SnowballiD· 1 shared Andreas LiebiD· 1 shared Claudia Di BerardinoiD· 1 shared Jonathan H. CornfordiD· 1 shared Luca MassiminoiD· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersNeuroscience

Dimitri Michael KullmannORCID

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2 papers

Recent·Most cited

Developmental instability of CA1 pyramidal cells in Dravet Syndrome

Steffan P. Jones, Nathanael O’Neill, Sharon Muggeo, Gaia Colasante, Dimitri Michael Kullmann, Gabriele Lignani

This study investigates how loss of Scn1a affects CA1 pyramidal cell development and homeostatic plasticity in a Dravet Syndrome model before seizures occur.

bioRxiv · Sep 12, 2022 · PreprintNeuroscience

In vivo CRISPRa decreases seizures and rescues cognitive deficits in a rodent model of epilepsy

Gaia Colasante, Yichen Qiu, Luca Massimino, Claudia Di Berardino, Jonathan H. Cornford, Albert Snowball, Mikail Weston, Steffan P. Jones, Serena Gea Giannelli, Andreas Lieb, Stéphanie Schorge, Dimitri Michael Kullmann, Vania Broccoli, Gabriele Lignani

This study uses CRISPRa to increase Kv1.1 expression in mouse hippocampal neurons, reducing seizures and cognitive deficits in a temporal lobe epilepsy model.

Brain · Jan 30, 2020Peer-reviewedNeuroscience