Author

V. Siddartha Yerramilli

University of WashingtonORCID 0000-0002-4562-682XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Organism:human· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Kyung Hyuk KimiD· 2 shared Aleksandra Nita‐LazariD· 1 shared Fadila Bouamr· 1 shared Forrest H. HoytiD· 1 shared Herbert M. SauroiD· 1 shared Juraj KabátiD· 1 shared Kevin M. RoseiD· 1 shared Kiri ChoiiD· 1 shared

Activity by Year

2017-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersSynthetic Biology

Kyung Hyuk KimORCID

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3 papers

Recent·Most cited

Human ESCRT-I and ALIX function as scaffolding helical filaments in vivo

Stephanie J. Spada, Kevin M. Rose, Paola Sette, Sarah K. O’Connor, Vincent Dussupt, V. Siddartha Yerramilli, Kunio Nagashima, Virginie Helle Sjoelund, Phillip Cruz, Juraj Kabát, Sundar Ganesan, Margery G. Smelkinson, Aleksandra Nita‐Lazar, Forrest H. Hoyt, Suzanne Scarlata, , Fadila Bouamr

This study shows ESCRT-I and ALIX form helical filaments in vivo, serving as structural scaffolds and ESCRT-III assembly templates for membrane scission and viral budding.

bioRxiv · May 1, 2024 · PreprintCell Biology

Labeling RNAs in live cells using malachite green aptamer scaffolds as fluorescent probes

V. Siddartha Yerramilli, Kyung Hyuk Kim

The paper develops MGA scaffolds to enhance fluorescence signals for RNA labeling in live cells, achieving up to 20-fold brighter signals than baseline.

ACS Synthetic Biology · Mar 7, 2018Peer-reviewedSynthetic Biology

Context-Dependent Genetic Regulation

Kyung Hyuk Kim, V. Siddartha Yerramilli, Kiri Choi, Herbert M. Sauro

The paper shows that genetic regulation at the population level depends on cell-to-cell variability in regulatory factor concentrations and the 5' UTR of the regulator gene.

bioRxiv · Aug 9, 2017 · PreprintSynthetic Biology