Author

Rebecca L. Buckland

Australian National UniversityORCID 0000-0002-4569-6852Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1

Frequent Co-Authors

Anne Brüstle· 2 shared Jessica A. PettittiD· 2 shared Alexandre RCom-H’Cheo-Forgues· 1 shared Anselm EndersiD· 1 shared Christopher Richard ParishiD· 1 shared Cynthia M. TurnbulliD· 1 shared Dominik SpensbergeriD· 1 shared Fiona D. BallardiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersImmunology

Anne Brüstle

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2 papers

Recent·Most cited

Selective alteration to CD4 T cell differentiation by heterozygous IRF4L116R protects against neuroinflammation

Rebecca A. Jaeger, Nadia A. Roberts, Cynthia M. Turnbull, Sandali Seneviratne, Rebecca L. Buckland, Dominik Spensberger, Jessica A. Pettitt, Fiona D. Ballard, Anne Brüstle, Anselm Enders

This study shows that a heterozygous IRF4L116R mutation selectively impairs CD4 T cell differentiation into Th1, Th17, and Treg subsets, protecting against neuroinflammation without affecting overall T cell activation or memory.

bioRxiv · Jun 25, 2025 · PreprintImmunology

Alpha Synuclein Induced Immune Response Triggers Parkinson's Disease Like Symptoms

Rebekah G. Parkinson, Tony Xu, Jacob Martin, Zizheng Xian, Ilvana Ziko, Jessica A. Pettitt, Alexandre RCom-H’Cheo-Forgues, Rebecca L. Buckland, Sarah L. Gordon, Christopher Richard Parish, Anne Brüstle, Nathalie Dehorter

This study shows that autoimmune response to alpha-synuclein antigen causes Parkinson's disease-like symptoms in mice through immune cell infiltration and inflammation.

bioRxiv · May 27, 2024 · PreprintNeuroscience